Fig. 4
From: TDP-43 seeding activity in the olfactory mucosa of patients with amyotrophic lateral sclerosis
αSyn_SAA results for OM samples from sporadic MND cases. αSyn_SAA showed seeding activity in 9% of sALS cases and 11% of bALS cases, 67% of MSA cases, 100% of DLB cases and 33% of AD cases. No seeding activity was observed in the PLS, FOSMN or CTRL samples. Abbreviations: sALS = spinal-onset amyotrophic lateral sclerosis; bALS = bulbar-onset amyotrophic lateral sclerosis; PLS = primary lateral sclerosis; FOSMN = facial onset sensory and motor neuronopathy; MSA = multiple system atrophy; DLB = dementia with Lewy body; AD = Alzheimer's disease; CTRL = controls; AU = arbitrary units; h = hours